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URL:https://lectures.london/imperial-college/the-bioengineering-lecture-20
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X-WR-CALNAME:Lectures London
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UID:09fe3ae1-d3ed-4248-8c91-7be7442cd3a8
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DTSTAMP:20261007T121914
DTSTART:20261012T163000
DTEND:20261012T173000
SUMMARY:The Bioengineering  Lecture 2026
LOCATION:Imperial College: Lecture Theatre B10\, Molecular Sciences Resear
 ch Hub (MSRH)
DESCRIPTION:About the Bioengineering Lecture\nThe Bioengineering Lecture i
 s the Department of Bioengineering’s flagship lecture\, bringing our com
 munity together to hear from a leading international researcher working at
  the forefront of their field.\nThis year\, we welcome Professor Julia Vor
 holt\, Professor of Microbiology at ETH Zurich\, whose laboratory studies 
 plant microbiomes\, one-carbon metabolism\, and endosymbioses.\nThe lectur
 e will be followed by a drinks reception\, giving attendees the opportunit
 y to meet Professor Vorholt and continue the conversation with colleagues 
 from the university.\n\nEngineering Endosymbioses Through Single-Cell Impl
 antation\nAbstract\nEndosymbiosis\, in which one organism lives inside ano
 ther\, has profoundly shaped the evolution of complex life forms. By intim
 ately entangling two organisms\, it enables hosts to acquire metabolic cap
 abilities and expand into new niches. This interlinked lifestyle requires 
 extensive synchronisation and co-adaptation of the partners with regard to
  immunity\, metabolism\, replication\, and vertical transmission\, yet how
  such partnerships begin and stabilise remains elusive.\nWe have developed
  a single-cell approach using fluidic force microscopy (FluidFM) to transp
 lant mitochondria and\, building on this technology\, to induce and study 
 endosymbioses by delivering bacteria into host cells. In a fungal host\, i
 mplanted bacteria established a heritable endosymbiosis that\, under susta
 ined selection\, became more stable over generations with fitness gains. T
 hese engineered endosymbioses offer a window into how cellular partnership
 s arise\, and a route to designing new ones.\nBiography\nJulia Vorholt is 
 Professor of Microbiology at the Department of Biology\, ETH Zurich\, Swit
 zerland. \nShe studied biology at the Universities of Bonn and Marburg and
  carried out her doctoral work at the Max Planck Institute for Terrestrial
  Microbiology in Marburg\, Germany. Following postdoctoral research at the
  University of Washington in Seattle\, USA\, she led research groups at th
 e MPI Marburg and subsequently at the CNRS in Toulouse\, France. She joine
 d ETH Zurich as Associate Professor in 2006 and has been Full Professor si
 nce 2012. Since 2020\, she has been Co-Director of the Swiss National Cent
 re of Competence in Research (NCCR) Microbiomes. \nShe is an elected membe
 r of the European Molecular Biology Organization (EMBO)\, the Academia Eur
 opaea and the German National Academy of Sciences Leopoldina\, and an inte
 rnational member of the US National Academy of Sciences. \nHer awards incl
 ude the Otto Hahn Medal\, the Feodor Lynen Medal and the Novonesis Biotech
 nology Prize\, as well as three ERC Advanced Grants. Her laboratory studie
 s and engineers plant microbiomes\, one-carbon metabolism and endosymbiose
 s\, and develops fluidic force microscopy (FluidFM) for single-cell manipu
 lation.
URL;VALUE=URI:https://www.imperial.ac.uk/events/211811/the-bioengineering-
 lecture-2026/
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